Distinguished researcher of the Hebei University School of Basic Medical Sciences, once served as director of the Key Laboratory of Neurobiology of the Chinese Academy of Sciences, Shanghai Academy of Life Sciences, professor and vice president of the School of Life Sciences in Shanghai University. He has successively served as the leader of the sub projects of the National "973" Project "Basic Research on Brain Function and Major Brain Diseases" and "Dynamic Balance Regulation of Brain Function". He has long been engaged in pharmacological and toxicological research on ion channels and related modulators/ligands of biological membranes. In particular, his group hasconducted systematic research on the biochemical and physiological activities of domestically produced resource specific natural membrane channel modulators and blockers, as well as the integration and regulation of membrane channel pharmacological function and toxicology, forming a certain characteristic advantage in the international academic research field. He served as Vice Chairman of the Chinese Society of Neuroscience, Executive Director of the Chinese Society of Biophysics, Deputy Editor in Chief of the Journal of Physiology, Editorial Board Member of Biophysics Journal, Neuroscience Bulletin, and Chemistry of Life.